Uterine Cancer Research Results and Study Updates
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More Immunotherapy Options Approved for Treating Endometrial Cancer
People with advanced endometrial cancer now have new FDA-approved treatment options: pembrolizumab and durvalumab, paired with chemotherapy, for tumors with a genetic change called mismatch repair deficiency. The agency also expanded the approved uses of dostarlimab for the disease.
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Immunotherapy’s Role in Treating Endometrial Cancer Expected to Grow
In two clinical trials, combining immune checkpoint inhibitors with standard chemotherapy substantially increased how long people with advanced endometrial cancer lived without their cancer worsening, particularly those with dMMR or MSI-high tumors.
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Trastuzumab May Improve Survival in Women with Rare Endometrial Cancer
For some women with HER2-positive uterine serous carcinoma, a rare type of endometrial cancer, treating them with trastuzumab (Herceptin) and chemotherapy may help them live longer, according to updated results from a small clinical trial.
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Women Experience More Side Effects from Pelvic Radiation than Realized
Women with cervical or uterine cancer who received radiation to the pelvic region reported side effects much more often using an online reporting system called PRO-CTCAE than they did during conversations with their clinicians, a new study shows.
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Can Some Women Treated for Endometrial Cancer Forgo Radiation after Surgery?
Some women with endometrial cancer may be able to receive less intensive treatment, chemotherapy and no radiation, without increasing their risk of the disease recurring within 5 years, according to the results of a randomized clinical trial.
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Study Shows Incidence Rates of Aggressive Subtypes of Uterine Cancer Rising
An NCI-led study shows rates for aggressive subtypes of uterine cancer rose rapidly among women ages 30 to 79 from 2000–2015. The findings, published in the Journal of Clinical Oncology, also reveal racial disparities in incidence and survival rates.
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Study Provides Closer Look at Postmenopausal Bleeding and Endometrial Cancer
A new study has found that 90% of postmenopausal women diagnosed with endometrial cancer reported vaginal bleeding before their diagnosis. Approximately 9% of postmenopausal women who saw a doctor for bleeding, the study showed, later received an endometrial cancer diagnosis.
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Study Shows Experimental Screening Test Can Detect Endometrial and Ovarian Cancers
Scientists have struggled to come up with a simple test to detect endometrial and ovarian cancers early, when they are most likely to respond to treatment. Can a liquid biopsy test called PapSEEK change that?
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Endometrial Cancer Incidence Rising in the US and Worldwide
Diagnoses of endometrial cancer have increased worldwide in recent years, with rates rising in more than half of the 43 countries studied during the decade ending around 2010, a team of international researchers has shown.