Atezolizumab

FDA label information for this drug is available at DailyMed.

Use in Cancer

Atezolizumab is approved to treat:

• Breast cancer that is triple negative and has the PD-L1 protein. It is used with paclitaxel albumin-stabilized nanoparticle formulation in adults whose cancer is locally advanced, metastatic, or cannot be removed by surgery.
• Non-small cell lung cancer that has metastasized. It is used:
  • In adults whose disease has gotten worse during or after treatment with platinum chemotherapy. For patients whose cancer has a mutation in the epidermal growth factor receptor (EGFR) gene or anaplastic lymphoma kinase (ALK) gene, atezolizumab is used if their disease has gotten worse after treatment with FDA-approved therapy for these mutations.
  • With bevacizumab, paclitaxel, and carboplatin as first-line therapy in adults with non-squamous disease without a mutation in the EGFR gene or ALK gene.
• Urothelial carcinoma (a type of bladder cancer) that is locally advanced or has metastasized. It is used in:
  • Adults whose cancer has the PD-L1 protein and cannot be treated with cisplatin.
  • Adults whose cancer cannot be treated with platinum chemotherapy or has gotten worse during or after treatment with platinum chemotherapy.

Atezolizumab is also being studied in the treatment of other types of cancer.

More About Atezolizumab

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Atezolizumab - A lay language summary of important information about this drug that may include the following:

• warnings about this drug,
• what this drug is used for and how it is used,
• what you should tell your doctor before using this drug,
• what you should know about this drug before using it,
• other drugs that may interact with this drug, and
• possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Research Results and Related Resources

Immunotherapy Effective in Alveolar Soft Part Sarcoma

Atezolizumab Approved for Initial Treatment of Metastatic Lung Cancer

For Small Cell Lung Cancer, Immunotherapy Drug Finally Brings Improved Survival

FDA Alters Approved Use of Two Checkpoint Inhibitors for Bladder Cancer

Targeted Cancer Therapies

FDA Approves Three Immunotherapy Drugs for Patients with Bladder Cancer

Clinical Trials Accepting Patients

Find Clinical Trials for Atezolizumab - Check for trials from NCI's list of cancer clinical trials now accepting patients.