This page contains brief information about cyclophosphamide and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
FDA label information for this drug is available at DailyMed.
Use in Cancer
Cyclophosphamide is approved to be used alone or with other drugs to treat:
- Acute lymphoblastic leukemia (ALL) in children.
- Acute monocytic leukemia.
- Acute myeloid leukemia (AML).
- Breast cancer.
- Chronic granulocytic leukemia.
- Chronic lymphocytic leukemia (CLL).
- Chronic myelogenous leukemia (CML).
- Hodgkin lymphoma. It is used in patients with stage III or stage IV disease.
- Multiple myeloma.
- Mycosis fungoides (a type of cutaneous T-cell lymphoma) that is advanced.
- Neuroblastoma that is disseminated.
- Non-Hodgkin lymphoma (NHL). It is used in patients with stage III or stage IV NHL, including the following types:
- Lymphocytic lymphoma (nodular or diffuse).
- Mixed-cell type lymphoma.
- Histiocytic lymphoma.
- Burkitt lymphoma.
- Ovarian cancer.
Cyclophosphamide is also being studied in the treatment of other types of cancer.
More About Cyclophosphamide
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Cyclophosphamide Injection and Cyclophosphamide Tablet - Lay language summaries of important information about these drugs. MedlinePlus information may include the following:
- warnings about the drug,
- what the drug is used for and how it is used,
- what you should tell your doctor before using the drug,
- what you should know about the drug before using it,
- other drugs that may interact with the drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Clinical Trials Accepting Patients
Find Clinical Trials for Cyclophosphamide - Check for trials from NCI's list of cancer clinical trials now accepting patients.