cyclophosphamide
View Patient InformationA synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death.
| Synonym: | Ciclofosfamida ciclofosfamide Claphene CP monohydrate cyclophospham cyclophosphamid monohydrate cyclophosphamide monohydrate cyclophosphamidum cyclophosphan cyclophosphanum Cytophosphane Genoxal Mitoxan neosar Syklofosfamid |
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| Foreign brand name: | Carloxan Cicloxal CYCLO-cell Cycloblastin Cycloblastine Cyclostin Cyclostine Cytophosphan Fosfaseron Genoxal Genuxal Ledoxina |
| Abbreviation: | CTX |
| Code name: | Asta B 518 B-518 WR- 138719 WR-138719 |
| Chemical structure: | 1-bis(2-chloroethyl)-amino-1-oxo-2-aza-5-oxaphosphoridin monohydrate 2-[bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate 2-[bis(b-chloroethyl)amino]-1-oxa-3-aza-2-phosphacyclohexane-2-oxide monohydrate 2-[di(chloroethyl)amino]-1-oxa-3-aza-2-phosphacyclohexane 2-oxide monohydrate bis(2-chloroethyl)phosphamide cyclic propanolamide ester monohydrate bis(2-chloroethyl)phosphoramide cyclic propanolamide ester monohydrate N,N-bis(2-chloroethyl)-N'-(3-hydroxypropyl)phosphorodiamidic acid intramolecular ester monohydrate N,N-bis(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide monohydrate N,N-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide monohydrate N,N-bis(b-chloroethyl)-N',O-trimethylenephosphoric acid ester diamide monohydrate N,N-bis(beta-chloroethyl)-N',O-propylenephosphoric acid ester diamide monohydrate N,N-bis(beta-chloroethyl)-N',O-trimethylenephosphoric acid ester diamide monohydrate |