This page contains brief information about dostarlimab-gxly and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
FDA label information for this drug is available at DailyMed.
Use in Cancer
Dostarlimab-gxly is approved treat adults with mismatch repair deficient (dMMR) cancer that has come back or is advanced, including:
- Endometrial cancer that was treated with platinum chemotherapy, but it did not work or is no longer working.
- Solid tumors that got worse during or after other treatment and cannot be treated with other therapies.¹
¹This use is approved under FDA’s Accelerated Approval Program. As a condition of approval, confirmatory trial(s) must show that dostarlimab-gxly provides a clinical benefit in these patients.
Dostarlimab-gxly is also being studied in the treatment of other types of cancer.
More About Dostarlimab-gxly
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Dostarlimab-gxly - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Research Results and Related Resources
Immunotherapy and… Nothing Else? Studies Test Potential Paradigm Shift in Cancer Treatment
Cancer Immunotherapies Don’t Work for Everyone: HLA Gene May Explain Why
Clinical Trials Accepting Patients
Find Clinical Trials for Dostarlimab-gxly - Check for trials from NCI's list of cancer clinical trials now accepting patients.