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This page contains brief information about pembrolizumab (Keytruda) and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

US Brand Name(s)
FDA Approved

FDA label information for this drug is available at DailyMed.

Use in Cancer

Pembrolizumab is approved to treat:

¹This use is approved under FDA’s Accelerated Approval Program. As a condition of approval, confirmatory trial(s) must show that pembrolizumab provides a clinical benefit in these patients.

Pembrolizumab is also being studied in the treatment of other types of cancer.

More About Pembrolizumab

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Pembrolizumab - A lay language summary of important information about this drug that may include the following:

  • warnings about this drug,
  • what this drug is used for and how it is used,
  • what you should tell your doctor before using this drug,
  • what you should know about this drug before using it,
  • other drugs that may interact with this drug, and
  • possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Research Results and Related Resources

Pembrolizumab Approved for Some Patients with Advanced Esophageal Cancer

New Drugs, New Side Effects: Complications of Cancer Immunotherapy

Targeted Therapy–Immunotherapy Combinations Effective for Advanced Kidney Cancer

Pembrolizumab Now Second Immunotherapy Approved to Treat Merkel Cell Carcinoma

Exosomes May Help Tumors Evade Immune System

Combination of Immunotherapy Drugs Approved for Metastatic Colorectal Cancer

New Immunotherapy Option Approved for Cervical Cancer, Rare Lymphoma

FDA Alters Approved Use of Two Checkpoint Inhibitors for Bladder Cancer

Can Age Affect Response to Immune Checkpoint Inhibitors?

Immunotherapy Drugs Expand Treatment Options for Advanced Lung Cancer

For Rare Melanoma, Checkpoint Inhibitors May Hold Substantial Promise

Pembrolizumab Secures FDA Approval in Stomach Cancer

FDA Approves Pembrolizumab for Tumors with Specific Genetic Features

FDA Expands Approval of Pembrolizumab for First-Line Treatment of Non-Small Cell Lung Cancer

FDA Approves Pembrolizumab for Hodgkin Lymphoma

Pembrolizumab Shows Promise in Patients with Rare Form of Skin Cancer

Lung Cancer Precision Medicine Trials: Adapting to Progress

Pembrolizumab Improves Progression-Free Survival in Patients with Ipilimumab-Resistant Melanoma

The Playing Field for Cancer Checkpoint Inhibitors Is Expanding

Pembrolizumab Improves Overall Survival in Patients with Advanced Melanoma

Trial Yields Positive Data on Pembrolizumab for Lung Cancer, Potential Response Biomarker

New Therapies Are Changing the Outlook for Advanced Melanoma

Targeted Cancer Therapies

Clinical Trials Accepting Patients

Find Clinical Trials for Pembrolizumab - Check for trials from NCI's list of cancer clinical trials now accepting patients.

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