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Cancer Immunoprevention Network (CIP-Net)

Cancer Immunoprevention Network (CIP-Net) image with a purple shield in front of a lavender ribbon representing cancer

An emerging scientific opportunity is the development of approaches that leverage the immune system to prevent cancers. Further, an NCI Board of Scientifc Advisors (BSA) Ad Hoc Working Group encouraged fostering “novel and innovative research designs….to expedite progress in precision prevention.”

The Cancer Immunoprevention Network (CIP-Net), supported by DCB and the NCI Division of Cancer Prevention, is advancing a deeper understanding of basic mechanisms of immunoprevention, promoting the discovery of novel immunoprevention strategies, and fostering a community of cancer immunoprevention researchers.

Additional details about the network can be found on NCI Division of Cancer Prevention webpages about CIP-Net. 
 

CIP-Net News

CIP-Net Podcast Episode 1 - What Is Cancer Immunoprevention? A Conversation on Preventing Cancer Before It Starts

Drs. Bodour Salhia and Robert Samstein discuss the science behind cancer immunoprevention, current opportunities and challenges in the field, and the importance of translating advances in research into meaningful approaches for patients and communities.

CIP-Net Community Engagement

The CIP-Net Community Engagement Working Group, comprised of CIP-Net patient advocates, trainees, and investigators, created an infographic to be broadly shared to raise awareness and understanding of cancer immunoprevention.

Infographic explaining cancer immunoprevention, including how immune surveillance may prevent cancer development, key immunologic mechanisms, prevention strategies and evidence, current challenges, and a pathway toward personalized cancer prevention.

This infographic was created by the CIP-Net Community Engagement Working Group to show how the immune system may be leveraged to reduce cancer risk.

View and Print Infographic

CIP-Net Digital Media

DCB Contact for CIP-Net

For additional information about CIP-Net, please contact Dr. Lillian Kuo.

Funded Projects

CIP-Net Research Projects (UG3/UH3)

InstitutionPrincipal Investigator(s)Project Title
Columbia University Health SciencesNicholas Arpaia, Tal DaninoEngineered probiotic bacteria for colorectal cancer immunoprevention and interception
Fred Hutchinson Cancer CenterMadhav V. Dhodapkar, Richard A. Flavell, Noah. W. PalmTargeting microbial triggers of gammopathy for immunoprevention
Icahn School of Medicine at Mount SinaiNina Bhardwaj, Aimee L. Lucas, Robert M. SamsteinImmune determinants modulating cancer development in Lynch Syndrome
Massachusetts General HospitalShadmehr DemehriImmunosurveillance of breast glands with oncogenic germline mutations
Mayo Clinic ArizonaPeter L. Bergsagel, Marta ChesiPreclinical studies for the immunoprevention of multiple myeloma
MD Anderson Cancer CenterIsabelle Bedrosian, Anjana Bhardwaj, Preethi H. GunaratneChimeric RNA driven neopeptide vaccine for prevention of breast cancer in germline BRCA1/2 carriers
University of ArizonaSally E. Dickinson, Clara Curiel-LewandrowskiInvestigating novel targets for topical immunoprevention of keratinocytic skin cancer
University of Missouri-ColumbiaHaval Shirwan, Esma S. YolcuDeveloping a novel agonist of CD137 for cancer immunoprevention

CIP-Net Resource Coordinating Center (U24)

InstitutionPrincipal Investigator(s)Project Title
Roswell Park Cancer CenterAlan D. Hutson, Steven M. Lipkin, Song LiuCancer Immunoprevention Network (CIP-Net) Resource Coordinating Center
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