Onco-Aging Consortium (OAC)
The OAC is a joint NCI and National Institute on Aging (NIA) program funded through RFA-20-040. It was established to support research addressing key questions regarding how hallmarks of aging lead to impaired cellular activities and alterations in the microenvironment that contribute to the development and outgrowth of cancer-initiating cells (CICs).
The OAC supports interdisciplinary teams that combine aging and cancer expertise with approaches to decipher the biological pathways during aging that contribute to cancer initiation.
OAC News and Highlights
OMF Scientist Highlight: Jennifer Trowbridge
Dr. Trowbridge is an Associate Professor at Jackson Laboratory. Her laboratory investigates the regulation of stem cells in the blood during normal development, aging, and leukemia. In her OAC research, she is examining the how aging contributes to clonal hematopoiesis and leukemia.
In the video of the 2021 Edward P. Evans Seminar in myelodysplastic syndrome (MDS) at Dana-Farber, she presents her work focusing on mechanisms of hematopoietic aging, clonal hematopoiesis, and the risk of myeloid malignancies.
OAC Kick-Off Meeting – Feb. 17-18, 2022