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Cancer Currents: An NCI Cancer Research Blog

A blog featuring news and research updates from the National Cancer Institute.

An illustrated banner to represent NCI's Cancer Currents research news blog. The design features interconnected scenes: a patient receiving care, a researcher in a lab, a tumor model, a laptop and mobile device displaying research articles, fitness activity, a clinical setting, and a researcher giving a scientific presentation. The background showcases rolling hills and abstract buildings.
  • A young black woman speaking with her doctor
    • By NCI Staff

    A study found that the risk of developing any of 26 chronic health problems was about 50% higher among cancer survivors who were diagnosed as adolescents and young adults, compared with their peers who did not have cancer.

  • Researcher on Computer Gene Fusions
    • By NCI Staff

    Fusion proteins drive the development of many cancers in children, yet little is known about their biology. NCI’s Fusion Oncoproteins in Childhood Cancers Consortium brings together experts from varied disciplines to investigate these cancers.

  • Illustration showing ovarian cancer starting in the fallopian tube
    • By NCI Staff

    A microRNA—a molecule made by cells to turn genes on and off—called miR-181a may help high-grade serous ovarian cancer form, a study has found. The scientists think the microRNA could potentially help doctors detect ovarian cancer earlier.

  • Wrench and socket on a graphic of DNA
    • By NCI Staff

    The gene-editing tool CRISPR is changing the way scientists study cancer, and may change how cancer is treated. This in-depth blog post describes how this revolutionary technology is being used to better understand cancer and create new treatments.

  • Person holding tube of blood with closeup showing DNA methylation
    • By NCI Staff

    Results from two studies show that a liquid biopsy that analyzes DNA in blood accurately detected kidney cancer at early and more advanced stages and identified and classified different types of brain tumors.

  • An image of the shelves that house the chemicals in NCI's Developmental Therapeutics Program.
    • By NCI Staff

    Two rediscovered drugs, bisantrene and brequinar, slowed the growth of acute myeloid leukemia in studies of mice. The drugs blocked the activity of a protein called FTO, killing cancer stem cells and helping the immune system attack the cancer.

  • Older African-American woman in consultation with a doctor.
    • By NCI Staff

    Three recently launched NCI-supported studies could help researchers better understand the causes of racial/ethnic disparities in ovarian cancer. The ultimate goal is to eliminate disparities and improve survival for all women with the disease.

  • Child Patient with Bear
    • By Norman E. Sharpless, M.D.

    Since launching the Childhood Cancer Data Initiative, NCI has undertaken a range of research activities to support this important effort. In this Cancer Currents post, NCI Director Dr. Norman Sharpless provides an update on these efforts.

  • A depressed Vietnam War USA military veteran has his head down while covering his face with his hand
    • By NCI Staff

    In a study of more than 50,000 veterans with lung cancer, those with mental illness who received mental health treatment—including for substance use—lived substantially longer than those who didn’t participate in such programs.

  • Diagram illustrating high tumor mutational burden (TMB) and the production of abnormal proteins from somatic mutations. At the top, a circular diagram represents genetic mutations. An arrow points downward to symbolize how these mutations lead to the creation of abnormal proteins. Below, these proteins are shown near a black line labeled "Tumor," representing their association with tumor cells.
    • By Norman E. Sharpless, M.D.

    FDA’s approval of pembrolizumab (Keytruda) to treat people whose cancer is tumor mutational burden-high highlights the importance of genomic testing to guide treatment, including for children with cancer, according to NCI Director Dr. Ned Sharpless.

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