Cancer Risk - Cancer Currents Blog
News about research on factors that affect cancer risk, including inherited genetic mutations, smoking/tobacco use, obesity, and infectious agents like HPV.
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Anal Cancer Incidence and Deaths Are Rising in the United StatesThe number of cases and deaths from anal cancer have been on the rise in the United States since 2001, according to a new study. The increases have been especially rapid in two segments of the population.
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MGUS to Myeloma: Study Suggests Risk of Progression Can ChangeA person’s risk of progressing from a benign condition called monoclonal gammopathy of undetermined significance (MGUS) to the blood cancer multiple myeloma can change over time, according to a new study.
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Could a Vaccine Prevent Colorectal Cancer in People with Lynch Syndrome?Findings from an NCI-funded study suggest a new vaccine approach may have the potential to prevent colorectal cancer in people with Lynch syndrome, an inherited condition that increases an individual's risk for developing certain types of cancer.
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Studying “Total Diet” and Its Impact on Health, Including Cancer RiskResearchers are shifting how they assess diet and cancer risk, looking beyond the impact of individual foods or nutrients on health, and taking a more holistic approach, considering dietary patterns across the lifespan.
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Vaping Pods Produce High Nicotine Levels in Young UsersAdolescents who use pod-style e-cigarettes had higher levels of nicotine in their bodies than is typically found in adolescents who smoke conventional cigarettes, a new study has found. The study's findings are concerning for several reasons.
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Liquid Biopsy May Predict Risk of Breast Cancer Returning Years LaterUsing a liquid biopsy to test for tumor cells circulating in blood, researchers found that, in women with breast cancer, the presence of these cells could identify women at risk of their cancer returning years later.
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Easing Concerns about Giving Research Study Participants Their Genetic Test ResultsDo cancer study participants want to receive their genetic test results? A recent study involving women with a history of breast cancer tested an approach for returning genetic research results and evaluated the impact those results had on the women.
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Molecular Switch Links High-Fat Diet to Prostate Cancer MetastasisA new study in mice has revealed a molecular link between a high-fat diet and the growth and spread of prostate cancer. The findings, the study leaders believe, raise the possibility that changes in diet could potentially improve treatment outcomes in some men.
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Incidence of Cancers of the Lower Stomach Increasing among Younger AmericansA type of cancer that occurs in the lower stomach has been increasing among some Americans under the age of 50, even though in the general population the incidence of all stomach cancers has been declining for decades, according to a new study.
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An Important Moment in Tobacco ControlNovember 26, 2017, marked a unique moment in US public health history, with the major US tobacco companies issuing the first in a series of court-ordered "corrective statements" about their products.
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Study Identifies Crucial Characteristic of High-Risk HPVBy comparing the genomes of women infected with a high-risk type of human papillomavirus (HPV), researchers have found that a precise DNA sequence of a viral gene is associated with cervical cancer.
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Large Study Verifies Cancer Risk for Women Carrying BRCA1 or BRCA2 MutationsResults from the first large prospective study of breast and ovarian cancer risk in women with inherited mutations in the BRCA 1 or BRCA2 genes confirm the high risks estimated from earlier, retrospective studies.
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Shifts Seen in Tobacco Product Types Purchased in USThe consumption of cigarettes, small cigars, and chewing tobacco has declined over the past 15 years, according to a new study. These declines were partially offset by a rise in consumption of large cigars, pipe tobacco, and snuff.
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The Global Economic Burden of Tobacco: An Interview with Dr. Mark ParascandolaNCI’s Dr. Mark Parascandola answers questions about The Economics of Tobacco and Tobacco Control, the latest in a series of monographs on tobacco use and tobacco control, which was co-written with the World Health Organization.
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Adolescents Who Wouldn’t Have Smoked May Be Drawn to E-CigarettesThe findings from a recent study suggest that adolescents are not just using e-cigarettes as a substitute for conventional cigarettes but that e-cigarettes are attracting new users to tobacco products.
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Inherited Mutations in DNA-Repair Genes Found in Advanced Prostate CancersResearchers estimate that nearly 12% of men with advanced prostate cancer have inherited mutations in genes that play a role in repairing damaged DNA.
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Setting the Stage for the Next Decade of Tobacco Control ResearchA new report from an NCI working group lays out recommended priorities to help shape the institute’s future tobacco control research portfolio.
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Improving Public Health through Increased Tobacco Regulation
NCI’s Dr. Robert Croyle discusses the Food and Drug Administration’s release of a rule that extends its regulatory authority over tobacco products to include cigars, e-cigarettes, hookah (waterpipe) tobacco.
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BRCA Testing Rates High in Young Women with Breast CancerTesting for genetic mutations strongly associated with an increased risk of breast cancer has risen dramatically among women younger than age 40 who are diagnosed with the disease, according to a new study.
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Mouse Study Points to Mechanism Linking Obesity and Colorectal Cancer RiskA missing hormone in obese mice may help explain a longstanding association between obesity and an increased risk of colorectal cancer in humans.