January 2023 - Cancer Currents Blog
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Zanubrutinib’s Approval Improves Targeted Treatment for CLL
FDA has approved zanubrutinib (Brukinsa) for chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) based on results from two clinical trials. In both trials, the drug, which blocks a protein called BTK, was more effective and caused fewer side effects than other treatments.
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Trial Suggests Expanded Role for Blinatumomab in Treating ALL
The immunotherapy drug blinatumomab (Blincyto) extends life for people with acute lymphoblastic leukemia who are in remission, even those with no signs of disease after initial treatment, a trial has found.
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Pausing Long-Term Breast Cancer Therapy to Become Pregnant Appears to Be Safe
Many young women who are diagnosed with early-stage breast cancer want to become pregnant in the future. New research suggests that these women may be able to pause their hormone therapy for up to 2 years as they try to get pregnant without raising the risk of a recurrence in the short term.
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Study Probes Awareness of Alcohol’s Link to Cancer
A study confirmed that most US adults aren’t aware of the link between alcohol consumption and cancer. Even among those surveyed who were aware, some believed risk varies by the type of alcohol.
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In Mouse Study, KRAS-Targeted Drug Shows Potential against Pancreatic Cancer
An experimental drug, MRTX1133, shrank tumors or halted their growth in several mouse models of human pancreatic cancer with KRAS G12D mutations, a new study shows. The models included one that is genetically engineered to closely mimic the human disease.
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A Safer, Better Treatment Option for Some Younger Women with Breast Cancer
For younger women with advanced breast cancer, the combination of ribociclib (Kisqali) and hormone therapy was much better at shrinking metastatic tumors than standard chemotherapy treatments, results from an NCI-funded clinical trial show.