May 2019 - Cancer Currents Blog
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Studying Genes and Proteins Together Sheds New Light on Colon CancerUsing novel proteogenomic techniques, scientists from NCI’s Clinical Proteomic Tumor Analysis Consortium have uncovered new features of colon cancer that may guide new treatment strategies.
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T-DM1 Approval Expanded to Include Some Women with Early-Stage HER2-Positive Breast CancerFDA has expanded the approved use of the drug ado-trastuzumab emtansine (Kadcyla), also called T-DM1, to include adjuvant treatment in some women with early-stage HER2-positive breast cancer.
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When Cancer Spreads to Bone, A Single Dose of Radiation Therapy May Control PainNew findings from a clinical trial suggest that a single dose of radiation therapy may control painful bone metastases as effectively as multiple lower doses of radiation therapy.
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Pediatric MATCH Study Finds More Targetable Genetic Changes than ExpectedAn early report from the NCI–COG Pediatric MATCH trial shows that 24% of young patients with advanced cancer who had their tumors tested for genetic changes were eligible to receive one of the targeted therapies being tested.
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Tagraxofusp Proves Effective for BPDCN, A Rare Blood CancerNew findings from a clinical trial of the drug tagraxofusp confirm its efficacy against the rare blood cancer blastic plasmacytoid dendritic cell neoplasm (BPDCN).
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Prostate Cancer Prevention and Finasteride: A Conversation with NCI’s Dr. Howard ParnesThe Prostate Cancer Prevention Trial showed that finasteride can reduce the risk of prostate cancer, but might increase the risk of aggressive disease. NCI’s Howard Parnes talks about subsequent findings and what they mean for men aged 55 and older.
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New Drugs, New Side Effects: Complications of Cancer ImmunotherapyThe expanding use of cancer immunotherapy has revealed a variety of side effects associated with this treatment approach. Researchers are now trying to better understand how and why these side effects occur and develop strategies for better managing them.
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Some Children with Liver Cancer May Need Less Chemotherapy, Study SuggestsSome children with liver cancer may need less chemotherapy than is typically used, new research suggests. The study included children and infants with hepatoblastoma whose tumors had been surgically removed when the disease was diagnosed.
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A Vaccine to Treat Non-Hodgkin Lymphoma Advancing in Clinical TrialsIn some people with non-Hodgkin lymphoma (NHL), treating a single tumor with an in situ vaccine can help to shrink, or eliminate, tumors in other parts of the body, findings from a small clinical trial suggest.