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pegfilgrastim

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A long-acting pegylated form of a recombinant therapeutic agent which is chemically identical to or similar to an endogenous human granulocyte colony-stimulating factor (G-CSF). Produced endogenously by monocytes, fibroblasts, and endothelial cells, G-CSF binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions. Conjugation of the cytokine with a branched polyethylene glycol molecule (pegylation) significantly increases its therapeutic half-life.
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Synonym:filgrastim SD-01
pegfilgrastim biosimilar HSP-130
pegfilgrastim biosimilar Nyvepria
pegfilgrastim biosimilar Pegcyte
pegfilgrastim biosimilar PF-06881894
pegfilgrastim biosimilar Udenyca
pegfilgrastim biosimilar Ziextenzo
pegfilgrastim-apgf
pegfilgrastim-bmez
pegfilgrastim-cbqv
pegfilgrastim-jmdb
pegylated G-CSF
pegylated GCSF
pegylated granulocyte colony stimulating factor
SD-01
SD-01 sustained duration G-CSF
tripegfilgrastim
US brand name:Fulphila
Neulasta
Nyvepria
Udenyca
Ziextenzo
Foreign brand name:Dulastin
Jinyouli
Neulastim
Neupopeg
Pegcyte
Code name:HSP-130
PF-06881894
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