decitabine

View Patient Information

A cytidine antimetabolite analogue with potential antineoplastic activity. Decitabine incorporates into DNA and inhibits DNA methyltransferase, resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication.

Check for active clinical trials using this agent View this agent in the NCI Thesaurus

Synonym:	5-aza-dCyd decitabine for injection deoxyazacytidine dezocitidine
US brand name:	Dacogen
Abbreviation:	5AZA DAC
Chemical structure:	2'-deoxy-5-azacytidine 4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one 5-aza-2-deoxycytidine 5-aza-2'-deoxycytidine 5-aza-2'deoxycytidine 5-azadeoxycytidine
IND number:	50733
NSC code:	127716

decitabine

Search NCI's Drug Dictionary