mesna
View Patient InformationA sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion.
| Synonym: | mercaptoethane sulfonate Mesnum |
|---|---|
| US brand name: | Mesnex |
| Foreign brand name: | Ausobronc Filesna Mesnil Mexan Mistabron Mistabronco Mitexan Mucofluid Mucolene Uromitexan Ziken |
| Abbreviation: | MSA |
| Code name: | D-7093 UCB 3983 |
| Chemical structure: | 2-mercaptoethanesulfonic acid, sodium salt sodium 2-mercaptoethane sulfonate |
| IND number: | 25232 |
| NSC code: | 113891 |