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4-nitroestrone 3-methyl ether

A synthetic derivative of estradiol. 4-nitroestrone 3-methyl ether inhibits estrogen sulfotransferase (EST), a progesterone-induced secretory endometrial enzyme which affects estrogen receptor levels. This agent has been shown to be an effective growth inhibitor of some chemically induced animal mammary tumors.
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Synonym:4-nitroestrone
Chemical structure:3-methoxy-4-nitro-estra-1,3,5(10)-trien-17-one
NSC code:321803
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