4-nitroestrone 3-methyl ether
A synthetic derivative of estradiol. 4-nitroestrone 3-methyl ether inhibits estrogen sulfotransferase (EST), a progesterone-induced secretory endometrial enzyme which affects estrogen receptor levels. This agent has been shown to be an effective growth inhibitor of some chemically induced animal mammary tumors.
| Synonym: | 4-nitroestrone |
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| Chemical structure: | 3-methoxy-4-nitro-estra-1,3,5(10)-trien-17-one |
| NSC code: | 321803 |