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18F-fluoromisonidazole

A radiofluorinated 2-nitroimidazole derivate with hypoxia-specific tracer activity. Misonidazole is reduced under hypoxic conditions and in reduced form covalently binds to macromolecules in hypoxic cells. 18F (fluorine-18) radiofluorination of misonidazole to form 18F-fluoromisonidazole allows radioisotopic imaging of reduced misonidazole bound to macromolecules in hypoxic cells.

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Synonym:	18F-MISO 18F-misonidazole
Abbreviation:	18F-FMISO FMISO

18F-fluoromisonidazole

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