pazopanib hydrochloride
View Patient InformationThe hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived growth factor receptor (PDGF-R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated.
| US brand name: | Votrient |
|---|---|
| Foreign brand name: | Pazopater |
| Code name: | GW786034B |
| Chemical structure: | 5-((4-((2,3-dimethyl-2h-indazol-6-Yl)methylamino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide monohydrochloride |