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tasisulam sodium

The sodium salt form of tasisulam, an acyl-sulfonamide compound with potential antiproliferative activity. Tasisulam activates, through an as of yet not fully elucidated mechanism, the intrinsic mitochondrial-mediated cell death pathway as manifested by decreased adenosine triphosphate (ATP), cytochrome C release, activation of caspases, loss of mitochondrial membrane potential, production of reactive oxygen species (ROS) and eventually apoptosis.

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Code name:	LY573636-sodium
Chemical structure:	benzamide, N-[(5-bromo-2-thienyl)sulfonyl]-2,4-dichloro-, sodium salt

tasisulam sodium

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