Skip to main content
An official website of the United States government
Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

heat-killed bacterium Mycobacterium obuense IMM-101

A suspension of heat-killed Mycobacterium (M.) obuense, a non-pathogenic and naturally-occurring bacterium, with potential immunomodulating and antineoplastic activities. Upon intradermal administration of heat-killed M. obuense IMM-101, the bacteria are able to activate the innate and adaptive immune system. Specifically, IMM-101 activates immature dendritic cells (DCs), which leads to the induction of a type-1 immune response (cDC1). This may induce a cytotoxic T-lymphocyte (CTL)-mediated immune response against cancer cells. It also activates macrophages and natural killer cells (NKs), gamma delta T (gdT) cells, and induces a type 1 T helper (Th1) cell immune response against cancer cells.
Check for active clinical trials using this agentView this agent in the NCI Thesaurus
Synonym:heat-killed mycobacterial product IMM-101
heat-killed Mycobacterium obuense NCTC 13365 IMM-101
Code name:IMM 101
IMM-101
IMM101
Search NCI's Drug Dictionary
Please enter up to 30 characters for your search