autologous cytotoxic T lymphocytes exposed to dendritic cells loaded with 6B11 anti-idiotype minibody
A preparation of autologous cytotoxic T lymphocytes (CTLs) that are exposed, ex vivo, to autologous dendritic cells (DCs) loaded with the anti-idiotype minibody 6B11, which mimics the epithelial ovarian tumor-associated antigen (TAA), OC166-9, with potential immunostimulatory and antineoplastic activities. Upon administration, the CTLs exposed to DCs loaded with 6B11 anti-idiotype minibody target and kill autologous ovarian cells expressing the TAA.
| Synonym: | 6B11 anti-idiotype minibody-pulsed DCs induced autologous CTLs autologous CTLs exposed to 6B11-OCIK autologous CTLs exposed to 6B11mini-ovarian-cytokine-induced-killer cells autologous CTLs induced with 6B11 anti-idiotype minibody-pulsed DCs autologous cytotoxic T cells induced by autologous dendritic cells loaded with 6B11 anti-idiotype minibody |
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