autologous ovarian cancer-specific antigens-pulsed dendritic cells Cellgram-DC
A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with ovarian cancer-specific antigen(s), with potential immunostimulatory and antineoplastic activities. Upon subcutaneous administration of the autologous ovarian cancer-specific antigens-pulsed DCs Cellgram-DC near the lymph nodes, the DCs stimulate a specific cytotoxic T-lymphocyte (CTL)-mediated immune response against the ovarian cancer cells expressing the antigens, resulting in tumor cell lysis.
Synonym: | autologous dendritic cells Cellgram-DC pulsed with ovarian cancer-specific antigens autologous ovarian cancer-specific antigens-pulsed DCs Cellgram-DC Cellgram-DC |
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