autologous prostate cancer-specific antigens-pulsed dendritic cells Cellgram-DC-PC
A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with prostate cancer (PC)-specific antigen(s), with potential immunostimulatory and antineoplastic activities. Upon administration of the autologous PC-specific antigens-pulsed DCs injected subcutaneously near the inguinal lymph nodes, the DCs stimulate a specific cytotoxic T-lymphocyte (CTL)-mediated immune response against the PC cells expressing the antigens, resulting in tumor cell lysis.
Synonym: | autologous dendritic cells Cellgram-DC-PC pulsed with prostate cancer-specific antigens autologous prostate cancer-specific antigens-pulsed DCs Cellgram-DC-PC Cellgram-DC-PC |
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