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abiraterone acetate

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An orally active acetate ester form of the steroidal compound abiraterone with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels.
US brand name:Yonsa
Zytiga
Code name:BR9004
BR9004-1
CB 7630
CB-7630
CB7630
JNJ-212082
Chemical structure:17-(3-pyridyl)-5,16-androstadien-3beta-acetate
androsta-5,16-dien-3-ol, 17-(3-pyridinyl)-, acetate (ester), (3beta)-
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