abiraterone acetate
View Patient InformationAn orally active acetate ester form of the steroidal compound abiraterone with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels.
US brand name: | Yonsa Zytiga |
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Code name: | BR9004 BR9004-1 CB 7630 CB-7630 CB7630 JNJ-212082 |
Chemical structure: | 17-(3-pyridyl)-5,16-androstadien-3beta-acetate androsta-5,16-dien-3-ol, 17-(3-pyridinyl)-, acetate (ester), (3beta)- |