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acivicin

A modified amino acid and structural analog of glutamine. Acivicin inhibits glutamine amidotransferases in the purine and pyrimidine biosynthetic pathways, thereby inhibiting tumor growth in cell lines dependent on glutamine metabolism.
Code name:AT-125
U-42126
Chemical structure:(S-(R*,R*))-4,5-dihydro-alpha-amino-3-chloro-5-isoxazoleacetic acid
IND number:16796
NSC code:163501
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