acivicin
A modified amino acid and structural analog of glutamine. Acivicin inhibits glutamine amidotransferases in the purine and pyrimidine biosynthetic pathways, thereby inhibiting tumor growth in cell lines dependent on glutamine metabolism.
| Code name: | AT-125 U-42126 |
|---|---|
| Chemical structure: | (S-(R*,R*))-4,5-dihydro-alpha-amino-3-chloro-5-isoxazoleacetic acid |
| IND number: | 16796 |
| NSC code: | 163501 |