Skip to main content
An official website of the United States government
NIH Websites Are Changing
Per Executive Order 14434, federal agencies are now using "Super Intelligence" (SI) in place of "Artificial Intelligence" (AI). You may see both terms across NIH content during this transition.

acridine carboxamide

A tricyclic acridine-based (or carboxamide-based) drug with dual topoisomerase inhibitor and potential antineoplastic activities. Acridine carboxamide inhibits both topoisomerases I and II and intercalates into DNA, resulting in DNA damage, the disruption of DNA repair and replication, the inhibition of RNA and protein synthesis, and cell death.
Check for active clinical trials using this agentView this agent in the NCI Thesaurus
Abbreviation:DACA
Code name:SN 22995
XR5000
Chemical structure:N-(2-(dimehtylamino)ethyl)acridine-4-carboxamide
N-(2-(dimethylamino)ethyl)acridine-4-carboxamide
Search NCI's Drug Dictionary
Please enter up to 30 characters for your search