Skip to main content
An official website of the United States government

activated polyethylene glycol/polyethyleneimine-based surgical sealant

A surgical sealant composed of activated polyethylene glycol (PEG) and polyethyleneimine (PEI) that can be used to seal tears in the dura during spinal surgery in order to prevent cerebrospinal fluid (CSF) leakage. It may also minimize dural adhesions and scarring by providing a protective shield between the dura and surrounding tissue.
Synonym:adherus autospray dural sealant
adherus autospray ET dural sealant
adherus dural in situ polymerizing sealant
adherus dural sealant
Search NCI's Drug Dictionary