Skip to main content

Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

Ad5-encoding IFNg SP-002

A replication deficient adenovirus type 5 (Ad5) vector encoding for the cytokine human interferon gamma (IFNg; IFN-gamma), with potential antineoplastic and immunomodulating activities. Upon intratumoral administration, Ad5-encoding IFNg SP-002 expresses human IFNg, which binds to and activates the cell-surface IFN-gamma receptor and may stimulate an antiproliferative natural killer (NK) cell response against tumor cells and induce tumor cell apoptosis.

Check for active clinical trials using this agent View this agent in the NCI Thesaurus

Synonym:	adenoviral vector Ad5-hIFNg SP-002 adenovirus-5 vector-encoding human interferon gamma SP-002
Code name:	SP 002 SP-002 SP002

Ad5-encoding IFNg SP-002

Search NCI's Drug Dictionary