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Ad5-encoding IFNg SP-002

A replication deficient adenovirus type 5 (Ad5) vector encoding for the cytokine human interferon gamma (IFNg; IFN-gamma), with potential antineoplastic and immunomodulating activities. Upon intratumoral administration, Ad5-encoding IFNg SP-002 expresses human IFNg, which binds to and activates the cell-surface IFN-gamma receptor and may stimulate an antiproliferative natural killer (NK) cell response against tumor cells and induce tumor cell apoptosis.
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Synonym:adenoviral vector Ad5-hIFNg SP-002
adenovirus-5 vector-encoding human interferon gamma SP-002
Code name:SP 002
SP-002
SP002
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