allogeneic anti-CD19 CAR-NK cells QN-019a
A preparation of allogeneic natural killer (NK) cells engineered to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) cluster of differentiation 19 (CD19), with potential immunomodulating and antineoplastic activities. Upon administration, the allogeneic anti-CD19 CAR-NK cells QN-019a recognize, bind to and induce selective cytotoxicity in CD19-expressing tumor cells. CD19 is a B-cell specific cell surface antigen overexpressed in B-cell lineage malignancies.
Synonym: | allogeneic CD19-targeting CAR-NK cells QN-019a |
---|---|
Code name: | QN 019a QN-019a QN019a |