allogeneic anti-CD20 CAR T cells LUCAR-20SP
A preparation of donor-derived T lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) cluster of differentiation 20 (CD20), with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic anti-CD20 CAR T cells LUCAR-20SP specifically recognize and kill CD20-expressing tumor cells. CD20, a non-glycosylated cell surface phosphoprotein, is a B-cell specific cell surface antigen expressed in B-cell lineage malignancies.
Synonym: | allogeneic anti-CD20 CAR-T cells LUCAR-20SP |
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Code name: | LUCAR 20SP LUCAR-20SP LUCAR20SP |