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allogeneic anti-CD7 CAR T cells 4SCAR7U

A preparation of allogeneic, off-the-shelf (OTS), universal, gene-edited T lymphocytes expressing a fourth-generation chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) CD7, with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic anti-CD7 CAR T cells 4SCAR7U specifically target and kill CD7-expressing tumor cells. CD7 is a transmembrane glycoprotein expressed by T cells and natural killer (NK) cells and their precursors. It is expressed in the majority of lymphoblastic T-cell leukemias and lymphomas and in a subset of peripheral T-cell lymphomas.
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Synonym:4SCAR7U T cells
allogeneic anti-CD7 4SCAR-expressing T cells 4SCAR7U
allogeneic anti-CD7 CAR-T cells 4SCAR7U
allogeneic CD7-targeting universal CAR T cells 4SCAR7U
universal CD7-specific CAR gene-engineered T cells 4SCAR7U
Code name:4SCAR7U
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