allogeneic GM-CSF-secreting lethally irradiated prostate cancer vaccine
An allogeneic whole cell vaccine expressing human granulocyte macrophage-colony stimulating factor (GM-CSF) with potential antineoplastic activity. Tumor cells from prostate cancer patients are harvested and then genetically modified to secrete GM-CSF, an immune stimulatory growth factor that plays a key role in stimulating the body's immune responses against tumor cells. Because the vaccine is derived from allogenic cells, it has demonstrated a favorable side effect profile than other approaches of delivering long-lasting GM-CSF.
| Synonym: | allogeneic GM-CSF prostate cancer vaccine allogeneic prostate cancer vaccine, GM- CSF gene transduced allogeneic prostate cancer vaccine, GM-CSF gene transduced allogeneic prostate GVAX allogenic prostate GVAX GM-CSF gene transduced allogeneic prostate cancer vaccine GM-CSF prostate cancer vaccine GVAX allogeneic prostate cancer vaccine GVAX allogenic prostate cancer vaccine GVAX prostate GVAX prostate cancer vaccine prostate cancer vaccine, GM-CSF gene transduced prostate cancer vaccine, GVAX |
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