Altretamine
A synthetic cytotoxic s-triazine derivative similar in structure to alkylating agent triethylenemelamin with antineoplastic activity. Although the precise mechanism by which altretamine exerts its cytotoxic effect is unknown, N-demethylation of altretamine may produce reactive intermediates which covalently bind to DNA, resulting in DNA damage.
| Synonym: | hemel hexaloids hexamethylamine hexamethylmelamine |
|---|---|
| US brand name: | Hexalen |
| Foreign brand name: | Hexastat Hexinawas |
| Abbreviation: | HMM HXM |
| Code name: | ENT-50852 RB-1515 WR-95704 |
| Chemical structure: | 2,4,6-tris(dimethylamino)-s-triazine N,N,N',N',N",N"-hexamethyl-1,3,5-triazine-2,4,6-triamine N,n,n',N"N"-hexamethyl-1,3,5,-triazine-2,4,6,-triamine |
| IND number: | 954 |
| NSC code: | 13875 |