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Altretamine

A synthetic cytotoxic s-triazine derivative similar in structure to alkylating agent triethylenemelamin with antineoplastic activity. Although the precise mechanism by which altretamine exerts its cytotoxic effect is unknown, N-demethylation of altretamine may produce reactive intermediates which covalently bind to DNA, resulting in DNA damage.
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Synonym:hemel
hexaloids
hexamethylamine
hexamethylmelamine
US brand name:Hexalen
Foreign brand name:Hexastat
Hexinawas
Abbreviation:HMM
HXM
Code name:ENT-50852
RB-1515
WR-95704
Chemical structure:2,4,6-tris(dimethylamino)-s-triazine
N,N,N',N',N",N"-hexamethyl-1,3,5-triazine-2,4,6-triamine
N,n,n',N"N"-hexamethyl-1,3,5,-triazine-2,4,6,-triamine
IND number:954
NSC code:13875
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