NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

aminolevulinic acid hydrochloride
Patient Information
A topically administered metabolic precursor of protoporphyrin IX. After topical administration, aminolevulinic acid hydrochloride (ALA HCl) is converted to protoporphyrin IX (PpIX) which is a photosensitizer. When the proper wavelength of light activates protoporphyrin IX, singlet oxygen is produced, resulting in a local cytotoxic effect. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:ALA HCl
aminolevulinic acid HCl
amino-levulinic acid hydrochloride
delta-aminolevulinic acid hydrochloride
US brand name:Ameluz
Levulan Kerastick
Foreign brand name:Ameluz
Abbreviation:5-ALA HCl
Chemical structure:
  • 5-amino-4-oxopentanoic acid HCl
  • 5-Amino-4-oxopentanoic Acid Hydrochloride
  • d-Amino-Levulinic Acid HCl