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aminolevulinic acid hydrochloride

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The hydrochloride salt form of aminolevulinic acid, an aminoketone, used for local photosensitizing therapy. Aminolevulinic acid (ALA) is a metabolic pro-drug that is converted into the photosensitizer protoporphyrin IX (PpIX), which accumulates intracellularly. Upon exposure to light of appropriate wavelength (red, or blue), PpIX catalyzes oxygen to singlet oxygen, an intracellular toxin, which can further react to form superoxide and hydroxyl radicals. This leads to cellular cytotoxic effects.
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Synonym:aminolevulinic acid HCl
delta-aminolevulinic acid hydrochloride
US brand name:Ameluz
Levulan Kerastick
Foreign brand name:Alacare
Ameluz
Chemical structure:5-amino-4-oxopentanoic acid HCl
5-amino-4-oxopentanoic acid hydrochloride
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