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amonafide dihydrochloride

The dihydrochloride salt of amonafide, an imide derivative of naphthalic acid. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis.

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Synonym:	amonafide amonafide hydrochloride benzisoquinolinedione nafidimide
US brand name:	Quinamed
Abbreviation:	BIDA
Code name:	M-FA-142
Chemical structure:	1H-benz(de)isoquinoline-1,3(2H)-dione, 5-amino-2-(2-(dimethylamino)ethyl)

amonafide dihydrochloride

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