Skip to main content

Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

anbalcabtagene autoleucel

A preparation of autologous T lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) CD19, with potential immunostimulating and antineoplastic activities. Upon administration, anbalcabtagene autoleucel targets and binds to CD19-expressing tumor cells. This results in a cytotoxic T-lymphocyte (CTL) response against CD19-expressing tumor cells and tumor cell lysis. CD19 is a B-cell-specific cell surface antigen overexpressed in B-cell lineage tumors.

Check for active clinical trials using this agent View this agent in the NCI Thesaurus

Synonym:	autologous anti-CD19 CAR-T cells CRC01
Code name:	CRC 01 CRC-01 CRC01

anbalcabtagene autoleucel

Search NCI's Drug Dictionary