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anti-CA19-9 monoclonal antibody BNT321

A human immunoglobulin G1 (IgG1) monoclonal antibody directed against the carbohydrate antigen sialyl Lewis A (carbohydrate antigen 19-9; CA19-9), with potential antineoplastic activity. Upon administration, anti-CA19-9 monoclonal antibody BNT321 targets and binds to CA19-9, and kills CA19-9-expressing tumor cells through the induction of both complement-dependent cytotoxicity (CDC) and antibody-dependent cell-mediated cytotoxicity (ADCC). CA19-9 is overexpressed on a number of different tumor cell types, and plays a key role in tumor cell survival and metastasis.
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Synonym:anti-CA19-9 monoclonal antibody 5B1
HuMab 5B1
HuMab-5B1
Code name:5B1
BNT 321
BNT-321
BNT321
MVT-5873
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