anti-CD19/anti-CD3/anti-CD2 trispecific antibody PIT565
A trispecific T-cell engager and antibody targeting the tumor-associated antigen (TAA) CD19, the T-cell surface antigen CD3, and the T-cell co-stimulatory receptor CD2, with potential immunostimulating and antineoplastic activities. Upon administration, anti-CD19/anti-CD3/anti-CD2 trispecific antibody PIT565 targets and binds to CD3 and CD2 on T cells and CD19 expressed on tumor cells. The resulting cross-linkage may trigger a potent cytotoxic T-lymphocyte (CTL) response against CD19-expressing tumor cells. CD19 antigen is a B-cell specific cell surface antigen overexpressed in B-cell lineage malignancies.
Synonym: | anti-CD19/CD3/CD2 trispecific antibody PIT565 CD19 x CD3 x CD2 trispecific antibody PIT565 |
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Code name: | PIT 565 PIT-565 PIT565 |