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anti-CD19 CAR T cells AT101

A preparation of T lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD19 and containing, as of yet undisclosed co-stimulatory signaling domains, with potential immunostimulating and antineoplastic activities. Upon administration, anti-CD19 CAR T cells AT101 recognize and bind to CD19-expressing tumor cells, thereby inducing selective toxicity in CD19-expressing tumor cells. CD19 antigen is a B-cell specific cell surface antigen expressed in all B-cell lineage malignancies.

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Synonym:	anti-CD19 CAR-T cells AT101 anti-CD19 CAR-T cells AT101
Code name:	AT 101 AT-101 AT101

anti-CD19 CAR T cells AT101

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