anti-CD19 cord blood-derived CAR-NK cells
A preparation of cord blood (CB)-derived natural killer (NK) cells that have been genetically modified and transduced with a lentiviral vector to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) cluster of differentiation 19 (CD19), with potential immunomodulating and antineoplastic activities. Upon administration, the anti-CD19 CB-derived CAR-NK cells recognize, bind to and induce selective cytotoxicity in CD19-expressing tumor cells. CD19 is a B-cell specific cell surface antigen overexpressed in B-cell lineage malignancies.
Synonym: | CAR-NK019 CB anti-CD19 CAR NK Cells NK019 CB CAR NK cells NK019 CB CAR-NK019 |
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