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anti-CLDN6 CAR T cells

A preparation of T lymphocytes expressing a chimeric antigen receptor (CAR) targeting the cell surface protein claudin 6 (CLDN6), with potential immunostimulating and antineoplastic activities. Upon administration, the anti-CLDN6 CAR T cells specifically target and bind to CLDN6-expressing tumor cells, thereby selectively lysing CLDN6-expressing tumor cells. CLDN-6, a transmembrane tight-junction protein and embryonic antigen, is overexpressed on a variety of tumor cells but is not expressed on normal, healthy adult cells.

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Synonym:	anti-Claudin-6 CAR T cells Claudin 6-targeting CAR T cells CLDN6-targeting CAR T cells

anti-CLDN6 CAR T cells

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