anti-DLL3 CAR-NK cells SNC-115
A preparation of natural killer (NK) cells engineered to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) delta-like protein 3 (DLL3), with potential immunomodulating and antineoplastic activities. Upon administration, anti-DLL3 CAR-NK cells SNC-115 recognize, bind to and induce selective cytotoxicity in DLL3-expressing tumor cells. DLL3, a Notch pathway protein, is overexpressed on a variety of cancer cell types. It plays a key role in embryonic development and in tumor initiation and proliferation.
Synonym: | anti-DLL3 CAR NK cells SNC-115 anti-DLL3 CAR-natural killer cells SNC-115 |
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Code name: | SNC 115 SNC-115 SNC115 |