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anti-DLL3/CD3 bispecific antibody QLS31904

A bispecific antibody directed against both the tumor-associated antigen (TAA) delta-like protein 3 (DLL3) and the CD3 antigen found on T lymphocytes, with potential immunostimulating and antineoplastic activities. Upon administration, anti-DLL3/CD3 bispecific antibody QLS31904 binds to both the CD3 antigen on cytotoxic T lymphocytes (CTLs) and the DLL3 antigen on DLL3-expressing tumor cells. This activates and redirects CTLs to DLL3-expressing tumor cells, which results in the CTL-mediated cell death of DLL3-expressing tumor cells. DLL3, a Notch pathway protein, is overexpressed on a variety of cancer cell types. It plays a key role in embryonic development and in tumor initiation and proliferation.
Synonym:anti-DLL3/anti-CD3 bispecific antibody QLS31904
DLL3 x CD3 bispecific antibody QLS31904
Code name:QLS 31904
QLS-31904
QLS31904
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