anti-GPC3-CAR-T lymphocytes TAK-102
A preparation of T lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) specific for glypican-3 (GPC3), with potential immunostimulating and antineoplastic activities. Upon administration, anti-GPC3-CAR-T lymphocytes TAK-102 specifically targets and binds to GPC3-expressing tumor cells, resulting in tumor cell lysis. GPC3, a heparan sulfate proteoglycan and a member of the glypican family, is overexpressed on certain tumor cell types while minimally expressed on normal, healthy cells; GPC3 plays an important role in cellular proliferation and differentiation.
| Synonym: | anti-GPC3 CAR T cells TAK-102 CAR T cells TAK-102 glypican-3-specific CAR T cells TAK-102 |
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| Code name: | TAK 102 TAK-102 TAK102 |