anti-interleukin-2 receptor subunit gamma monoclonal antibody REGN7257
A monoclonal antibody targeted against interleukin-2 (IL-2) receptor subunit gamma (IL2RG; CD132; cytokine receptor common subunit gamma; gamma chain; gc), with potential immunomodulatory activity. Upon administration, anti-IL2RG monoclonal antibody REGN7257 targets and binds to the gamma subunit of the human IL-2 receptor (IL-2R) expressed on the surface of activated T lymphocytes, thereby inhibiting IL-2 binding and IL-2-mediated T-cell activation. This may block T-cell-mediated immune responses. IL2RG plays a role in both immune responses and interleukin signaling.
Synonym: | anti-cytokine receptor common subunit gamma monoclonal antibody REGN7257 anti-gamma chain receptor monoclonal antibody REGN7257 anti-IL2RG monoclonal antibody REGN7257 |
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Code name: | REGN 7257 REGN-7257 REGN7257 |