anti-KLK2 CAR T cells JNJ-75229414
A preparation of T lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting human kallikrein-2 (hK2; KLK2) expressed on tumor cells, with potential immunostimulating and antineoplastic activities. Upon administration, anti-KLK2 CAR T cells JNJ-75229414 target and bind to KLK2-expressing tumor cells, thereby inducing selective toxicity in KLK2-expressing tumor cells. KLK2 is overexpressed in certain tumors, including prostate adenocarcinoma.
Synonym: | anti-kallikrein-2 CAR T cells JNJ-75229414 KLK2 CAR-T cells JNJ-75229414 |
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Code name: | JNJ 75229414 JNJ-75229414 JNJ75229414 |