anti-MSLN CAR-T cells LCAR-M23
A preparation of Tl ymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) specific for the human tumor-associated antigen (TAA) mesothelin (MSLN), with potential immunomodulating and antineoplastic activities. Upon administration, the anti-MSLN CAR-T cells LCAR-M23 specifically target and kill MSLN-expressing tumor cells. Mesothelin, a cell surface glycoprotein involved in cell adhesion, is overexpressed in a variety of cancer cell types.
Synonym: | anti-mesothelin CAR T cells LCAR-M23 mesothelin-targeting CAR T cells LCAR-M23 |
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Code name: | LCAR M23 LCAR-M23 LCARM23 |