anti-MUC16 CAR T cells 27T51
A preparation of T lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) human mucin-16 (MUC16, cancer antigen 125; CA125; FLJ14303), with potential immunostimulating and antineoplastic activities. Upon administration, anti-MUC16 CAR T cells 27T51 recognize and bind to MUC16-expressing tumor cells, thereby inducing selective toxicity in MUC16-expressing tumor cells. MUC16, a member of the mucin family of glycoproteins, is overexpressed on a variety of cancer cell types.
Synonym: | anti-MUC16 CAR-T cells 27T51 anti-mucin-16 CAR T cells 27T51 |
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Code name: | 27T51 bbT 4015 bbT-4015 bbT4015 |