anti-STEAP1 CAR T cells
A preparation of T lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) six transmembrane epithelial antigen of the prostate 1 (STEAP1), with potential immunostimulating and antineoplastic activities. Upon administration, anti-STEAP1 CAR T cells recognize and bind to STEAP1-expressing tumor cells, thereby inducing selective toxicity in STEAP1-expressing tumor cells. STEAP1 is overexpressed in a variety of cancer cell types.
Synonym: | anti-STEAP1 CAR-T cells STEAP1 CAR-T cells STEAP1-targeting CAR T cells STEAP1-targeting CAR-T cells |
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