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apolizumab

A humanized monoclonal antibody directed against 1D10, a polymorphic determinant on the HLA-DR beta chain that is expressed on normal and neoplastic B cells. Apolizumab induces complement-mediated cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and apoptosis of 1D10 antigen-positive B cells in vitro.
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Synonym:1D10 anti-lymphoma antibody
1D1O anti-lymphoma antibody
MAbHu1D10
monoclonal antibody 1D10
monoclonal antibody Hu1D10
US brand name:Remitogen
Abbreviation:MOAB 1D10
MoAb Hu1D10
IND number:8308
9968
NSC code:710066
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